| . |
The ability of a nanobioglass-doped self-etching adhesive to re-mineralize and bond to artificially demineralized dentin.
Dent Mater. 2020 Nov 21;:
Authors: Abuna G, Campos P, Hirashi N, Giannini M, Nikaido T, Tagami J, Coelho Sinhoreti MA, Geraldeli S
Abstract
OBJECTIVE: To a self-etch adhesive doped with nano-bioglass and evaluate its ability to bond and re-mineralize artificially demineralized dentin.
METHODS: Experimental Si, Ca, Na and PO4 based nanobioglass particles were synthesized, doped into experimental self-etch adhesives, and divided into 3 groups: Clearfi SE2 (CSE2), experimental (EXC), and experimental doped with 10% of nanobioglass (ExNB). The adhesives were applied onto the caries-affected dentin (chemically simulated), and evaluated after 24 h and 28 days of immersion in simulated body fluid. The remineralization process was assessed using optical coherence tomography, nanoindentation, in situ zymography, transmission electron microscopy, confocal laser scanning microscopy, μ-tensile bond strength, and pH buffer.
RESULTS: The addition of nanobioglass particles into the experimental self-etch adhesives altered the μTBS in the short-term jeopardizing dentin bonding properties, when compared to the non-doped self-etch adhesive. The remineralization recovered the nanohardness, and volume lost by caries lesion (p = 0.02). Moreover, reduced the enzymatic activity (p = 1.24E-4) and formed new crystals within of the hybrid layer.
CONCLUSION: The use of nanobioglass was efficient to recover the properties of a caries affected dentin. Furthermore, the adhesive properties were not hampered and the probabilistic reliability increased.
[cite source='pubmed']33229040[/cite] – as supplied by publisher]